Advanced Daily Defense Serum
NEW
NEW
NEW
Advanced Daily Defense Serum
Skin type: All Skin Types
A daily antioxidant serum designed to visibly transform stressed sensitive skin, for stronger skin against daily stressors
- IMPROVE RADIANCE, PORES & FINE LINES: Formulated with Triple Hyaluronic Acid to hydrate and smooth the skin, and Niacinamide to help minimize the appearance of pores and enhance radiance
- POWERFUL ANTIOXIDANT COMPLEX: With Gallic‑AOX Power™, a complex of Gallic Acid and Vitamin E helps defend against oxidative stress
- DESIGNED FOR SENSITIVE SKIN: This powerful antioxidant serum is suitable for even the most sensitive skin, with a hypoallergenic, fragrance free and non-comedogenic formula
- DERMATOLOGIST RECOMMENDED FOR SENSITIVE SKIN
- EFFECTIVE AM/PM ROUTINE: Pair this AM serum with CETAPHIL Repair & Renew Serum overnight to help visibly improve the overall appearance of sensitive skin in 2 weeks(1) In-Use test (clinical grading, Asian and Caucasian panel): significant improvement in overall skin quality (sum of 9 graded scores: pores appearance, fine lines, scars, skin visible redness, pigmentation, dullness, laxity, oiliness and dryness) by 6% after 14 days, by 17% after 28 days and by 17% after 56 days.
FEATURES
Start your day with CETAPHIL Advanced Defense Serum to help defend your skin against day-to-day stress. Daily external stressors can impact the skin's natural repair and renewal process, which can lead to dryness, visible redness and breakouts. This AM face serum is designed to help strengthen sensitive skin against daily stressors for more radiant-looking skin. It's powered by Gallic-AOX , a powerful antioxidant complex of Gallic Acid and Vitamin E that boosts sensitive skin's defense against oxidative stress. It's also formulated with Triple Hyaluronic Acid to deeply hydrate and smooth skin, and Niacinamide to help minimize the appearance of pores and enhance radiance. This hypoallergenic and fragrance-free formula is suitable for even the most sensitive skin, and it won't clog pores. Pair with CETAPHIL Repair & Renew Serum overnight to help visibly improve the overall quality of stressed sensitive skin in 2 weeks(1).
THE ROUTINE
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FEAUTRED INGREDIENTS
GALLIC ACID AND VITAMIN E (GALLIC AOX POWER), HYALURONIC ACID, NIACINIMIDE
ALL INGREDIENTS
WATER, BUTYLENE GLYCOL, PEG/PPG-8/3 LAURATE, PENTYLENE GLYCOL, POLYGLYCERYL-4 CAPRATE, 1,2-HEXANEDIOL, NIACINAMIDE, EPIGALLOCATECHIN GALLATYL GLUCOSIDE, HYDROLYZED HYALURONIC ACID, ALLANTOIN, TOCOPHERYL ACETATE, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, SODIUM HYALURONATE, TOCOPHEROL, SODIUM GLUCONATE, CITRIC ACID
Find out more about our ingredients
Glycerin
Glycerin is a naturally occurring compound. It is a water-soluble emollient that softens and smooths skin. It also produces long-lasting moisturization by attracting water into the skin and helping to retain skin moisture, leaving it appearing healthy and youthful.
Niacinamide
Niacinamide or vitamin B3 is an essential vitamin for the skin with both antioxidants and hydrating properties. It locks in moisture effectively.
Tocopherol
Tocopherol or vitamin E has an antioxidant effect that helps protect the skin from surface free radical damage. It also soothes skin with a hydrating effect.
Hyaluronic Acid
Hyaluronic acid occurs naturally within the skin and gives skin natural plumpness and a silky-smooth texture. With age, natural hyaluronic acid decreases. Hyaluronic acid can boost skin elasticity and impressively retain moisture.
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Reviews
Rated 5 out of
5
by
MayS from
Love this morning serum
I’ve been using the Cetaphil AM serum for the past month and I absolutely love it! I apply it after washing my face in the morning, and it always feels so smooth on my skin. It leaves my skin super moisturized without being sticky which I really appreciate. I also love the glass bottle and the convenient applicator it comes with. Another big plus is that it’s fragrance free, which I always appreciate in skincare. I think the value for this product is great it’s not expensive and you get a decent amount of product that can last for a while.
So far, I’ve seen great results and I’m definitely going to keep using it.
Date published: 2026-03-01
Rated 5 out of
5
by
HarleyGrazianoH from
Nice nice
I've been using this product consistently and love how balanced it feels. The Vitamin E provides strong antioxidant protection while the hyaluronic acid and niacinamide keep my skin hydrated and plump. It absorbs quickly, layers well and feels gentle on sensitive skin. There is a slight clinical smell at first and resilts for fine lines and wrinkles will take a couple weeks- but overall my skin looks smoother and more radiant. I love the glass bottle and ir packaged very well. I did not have any breakouts with it!
Date published: 2026-03-01
Rated 4 out of
5
by
LaurenC from
Protects against free radicals!
The advanced daily defense serum is very hydrating and supports the skins barrier. My skin feels plump and glowy after using. I love that this protects against free radicals! I have acne prone skin and I think the vitamin E in this serum made me break out.
Date published: 2026-03-01